Man destined to get Alzheimer’s saved by accidental heat therapy
Doug Whitney (left, pictured with his son Brian in November 2022) is genetically predisposed to develop Alzheimer’s, but has so far dodged the condition Shelby Lum/Associated Press/Alamy A man in the US who was virtually guaranteed to get early-onset Alzheimer’s disease because of his genetics has somehow dodged it, possibly thanks to his inadvertent heat exposure while working as a mechanic in ship engine rooms. The case fits with growing evidence from studies in humans and other animals that suggest that heat therapy may protect against the condition. Doug Whitney’s family carries a variant of a gene called Presenilin 2, inherited from ancestors who have been traced back to a small, 18th-century Volga German village. Carriers of this mutation, which causes aberrant folding of proteins in the brain, almost always develop Alzheimer’s disease in their late 40s or early 50s. “My family has been devastated by this disease,” Whitney said in a press statement. “My mom had 13 brothers and sisters, and 10 died before they were 60 years old. It’s been a plague.” Despite …








