All posts tagged: Alters

How a year of regular exercise alters the biology of stress

How a year of regular exercise alters the biology of stress

A new year-long study reveals that engaging in regular aerobic exercise lowers long-term levels of a major stress hormone, which might help protect against heart disease and mood disorders. Published in the Journal of Sport and Health Science, the clinical trial demonstrates how meeting standard physical activity guidelines benefits our underlying stress biology. These results suggest that breaking a sweat provides lasting physiological relief from chronic stress. Peter Gianaros, a psychology researcher at the University of Pittsburgh, led the investigation alongside a team of health and neuroscience specialists. The research team wanted to understand if training the body to handle physical exertion also trains the brain and body to handle mental pressure. They designed a trial to observe these biological adaptations over an entire year. When a person works out, their heart rate rises and their body experiences a temporary form of physical stress. Over time, regular exercise makes the cardiovascular system more efficient at handling this physical load. Researchers have proposed a concept called the cross-stressor adaptation hypothesis to explain how this works. This …

Early life stress fundamentally alters alcohol processing in the brain

Early life stress fundamentally alters alcohol processing in the brain

Experiencing social isolation during early developmental years can lead to increased anxiety and a higher preference for alcohol later in life. A new study in rats shows that these early stressors physically alter how the brain responds to alcohol, specifically changing how the chemical dopamine is regulated in regions linked to reward processing. The findings were published in the journal Addiction Neuroscience. As children and teenagers navigate critical periods of brain development, social contact helps shape their neural circuits. Environmental stressors during this sensitive window can disrupt normal developmental trajectories. Experiencing isolation or neglect during youth can elevate the risk of mood disorders and substance use issues in adulthood. Researchers from Binghamton University and Brigham Young University wanted to understand the biological mechanisms behind this vulnerability. Lead author Gavin J. Vaughan and senior author Anushree N. Karkhanis, both affiliated with Binghamton University, focused on a brain structure called the ventral pallidum. The ventral pallidum is a small cluster of cells resting deep within the brain. It acts as a central hub for assessing the value …

Early exposure to a high-fat diet alters how the adult brain reacts to junk food

Early exposure to a high-fat diet alters how the adult brain reacts to junk food

Exposure to a diet heavy in fats and sugars during early development primes the brain to overreact to unhealthy foods in adulthood. This combination leads to high levels of inflammation and reduced adaptability within the brain’s main memory center. These molecular changes suggest that early nutritional environments have long-lasting effects on cognitive health, according to a recent study published in Nutritional Neuroscience. The physical makeup of the brain is not set in stone at birth. It constantly changes and adapts in response to life experiences. This feature of the nervous system is known as neural plasticity. Neural plasticity allows humans and animals to form new memories, learn new skills, and recover from physical injuries. To function properly, the brain relies on specific proteins that act as fertilizer for neural connections. One of these vital proteins is a growth factor that helps neurons survive and communicate. When the brain is healthy, these growth factors bind to specific receptors on the outside of brain cells. This continuous chemical dialogue allows the nervous system to adapt to new …

OpenAI alters deal with Pentagon as critics sound alarm over surveillance

OpenAI alters deal with Pentagon as critics sound alarm over surveillance

OpenAI CEO Sam Altman unveiled a reworked agreement with the Pentagon on Monday night governing the Defense Department’s use of its AI services, which he says provides stronger guarantees that the military won’t use OpenAI’s systems for domestic surveillance. The new agreement states that “the AI system shall not be intentionally used for domestic surveillance of U.S. persons and nationals,” according to a post on OpenAI’s website. OpenAI had faced some backlash as news of an initial agreement between the leading AI company and the Pentagon emerged Friday. Many observers claimed the original language shared on OpenAI’s website provided ample loopholes for the government to surveil Americans. The move comes after weeks of intense debate between rival AI company Anthropic and the Pentagon over how the military can use advanced AI systems. While the Defense Department had wanted Anthropic to agree to let the department use its systems for “any lawful purpose,” Anthropic maintained its systems could not be used for domestic surveillance or to control deadly autonomous weapons. Until last week, Anthropic was the …

Study of Buddhist Monks Finds Meditation Alters Brain Activity

Study of Buddhist Monks Finds Meditation Alters Brain Activity

If you’ve ever considered practicing meditation, you might believe you should relax, breathe, and empty your mind of distracting thoughts. Novices tend to think of meditation as the brain at rest, but a new international study concludes this ancient practice is quite the opposite: meditation is a state of heightened cerebral activity that profoundly alters brain dynamics. Researchers from the University of Montreal and Italy’s National Research Council recruited twelve monks of the Thai Forest Tradition at Santacittārāma, a Buddhist monastery outside Rome. In a laboratory in Chieti-Pescara, scientists analyzed the brain activity of these meditation practitioners using magnetoencephalography (MEG), technology capable of recording with great precision the brain’s electrical signals. The study focused on two classical forms of meditation: Samatha, a technique that focuses on sustained attention to a specific objective, often steady breathing, with the aim of stabilizing the mind and reaching a deep state of calm and concentration, and Vipassana, which is based on equanimous observation of sensations, thoughts, and emotions as they arise in order to develop mental clarity and a …