Early exposure to forever chemicals linked to altered brain genes and impulsive behavior in rats
A study on rats found that exposure to perfluorooctanesulfonic acid (PFOS) altered gene expression in the nucleus accumbens, hippocampus, and prefrontal cortex regions of the brain of their offspring. In turn, this may have led to impaired cognitive performance and more impulsive decision-making. The paper was published in Ecotoxicology and Environmental Safety. Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic chemicals widely used in industrial processes and consumer products due to their resistance to heat, water, and oil. One of these chemicals is perfluorooctanesulfonic acid, or PFOS, a legacy substance that was used for decades in products such as firefighting foams and stain-resistant coatings, as well as in certain manufacturing processes. It is often called a “forever chemical” because it breaks down extremely slowly and can remain in the environment for a very long time. Although the use of PFOS was largely discontinued in the early years of the 21st century, PFOS remains widely present in both the environment and the human body. PFOS resists metabolic breakdown, resulting in prolonged accumulation in the …








