Five common medications that make it harder to cope in the heat
Get the Well Enough newsletter with Harry Bullmore for tips on living a healthier, happier and longer life Get the Well Enough email with Harry Bullmore Get the Well Enough email with Harry Bullmore As temperatures rise, so does the risk of heat-related illness, especially for people taking certain prescription drugs. The body uses several mechanisms to regulate temperature: sweating, blood flow to the skin and fluid balance. But some commonly prescribed drugs interfere with these processes, making it harder to stay cool. Here are a few you should know about this summer: 1. Antidepressants Two specific types of antidepressants – selective serotonin reuptake inhibitors (SSRIs) and tricyclics (TCAs) – may make summer harder to cope with. They could even cause heat intolerance due to how they affect the body’s ability to sweat. Both these antidepressants are believed to partly work by affecting neurotransmitter levels in the brain – primarily serotonin and noradrenaline. However, they may also affect other neurotransmitters. For instance, TCAs can block acetylcholine, a neurotransmitter important for sweating. This may cause some …








