Co-occurring depression and cannabis use linked to less efficient brain networks
New research published in Drug and Alcohol Dependence provides evidence that experiencing depression symptoms alongside cannabis use is linked to less efficient communication across the brain compared to cannabis use alone. The study suggests that while cannabis use tends to increase overall connectivity in the brain, the presence of depression weakens this effect, resulting in a less integrated brain network. Scientists conducted this study to better understand the underlying biology of why cannabis use and depression frequently occur together. Heavy or chronic cannabis use might increase the risk of developing depression, while individuals experiencing depression often turn to cannabis to self-medicate. Both cannabis use and depression individually alter the way different areas of the brain communicate with each other. This baseline brain communication is known as resting-state functional connectivity, which refers to the brain activity that happens when a person is awake but not focused on a specific task. Prior studies have shown changes in resting-state connectivity in people who use cannabis and in those with depression, but the combined effect of both factors on …







