All posts tagged: infusion

Frailty can be eased with an infusion of stem cells from young people

Frailty can be eased with an infusion of stem cells from young people

Slow walking speed is a common feature of frailty Gordon Scammell/Loop Images/Universal Images/Getty Images An experimental stem cell therapy could treat frailty by targeting the condition at its biological roots. Frailty – which raises the risk of falls and infections – is typically only mitigated through lifestyle changes, like doing strength training and balance exercises. But now, it seems that a novel infusion of stem cells from young, healthy people into older individuals significantly improved their mobility. “Frailty is a major source of disability and diminished quality of life in older individuals,” says Joshua Hare at Longeveron, a biotechnology company in Miami, Florida. “There is a major unmet need to find biological treatments.” Hare and his colleagues at Longeveron are developing a therapy that they hope will target some of the underlying mechanisms of ageing, such as inflammation and impairment of the metabolic processes that make muscles contract. The therapy – called laromestrocel – is made up of mesenchymal stem cells that can develop into many different types of cells, including muscle and cartilage, taken …