A study examining subjective experiences after intranasal application of 5-MeO-DMT found that its effects peak 8-15 minutes after application. Consciousness-altering effects typically ended after 45-60 minutes. The research was published in Scientific Reports. 5-methoxy-N,N-dimethyltryptamine or 5-MeO-DMT is a naturally occurring psychedelic compound belonging to the tryptamine class. It is found in certain plants and in the venom of the Incilius alvarius (Sonoran Desert toad), as well as produced synthetically. The substance is known for producing extremely intense and short-lasting altered states of consciousness. Its effects typically include profound changes in perception, a strong sense of ego dissolution, and altered awareness of time and self. Compared to DMT, the effects of 5-MeO-DMT are less visual but more immersive and abstract. Users report the experience as emotionally powerful and sometimes overwhelming. Research interest in 5-MeO-DMT has increased due to its potential relevance for understanding consciousness and mental health. However, scientific evidence on its therapeutic effects and risks is still limited. Study author Anna O. Ermakova and her colleagues wanted to understand the experiences of individuals participating in …