Regaining Weight After Quitting Your GLP-1 Drug? A Simple Procedure Might Help, Study Says
By Dennis Thompson HealthDay ReporterMONDAY, April 27, 2026 (HealthDay News) — Regaining the weight you’ve just lost is a major risk for anyone who decides to stop taking Ozempic or Zepbound. But an experimental outpatient gut procedure might help people transition off their GLP-1 weight loss drug without packing on the pounds, according to new research scheduled for presentation at the Digestive Disease Week meeting in Chicago. This simple “gut reset” helped a small group of patients maintain up to 80% of their weight loss after they stopped taking tirzepatide (Mounjaro/Zepbound), researchers found. “As effective as GLP-1 medications are, many people stop taking them because of cost, side effects or simply not wanting to take a drug long-term,” said lead researcher Dr. Shelby Sullivan, director of the Endoscopic Bariatric and Metabolic Program at Dartmouth Health Weight Center in Lebanon, New Hampshire. “But if they stop these medications, weight regain occurs in the vast majority of patients, and the metabolic benefits are lost,” she said in a news release. “Finding a treatment that allows patients to …
