Shingles is linked to inflammation in the brain. Research shows how to cut dementia risk.
The shingles vaccine may significantly help protect older adults against dementia, a growing body of evidence shows. Limited time: Save 25% on NBC News subscription Get exclusive reporting, live Q&As and ad-free reading. Exactly how is unclear. The nervous system, however, likely holds clues. Shingles, a condition triggered by the reactivation of the varicella-zoster virus in the body, can cause a “war zone” of inflammation in the brain, said Dr. Jennifer Pauldurai, the medical director of the Inova Brain Health and Memory Disorders Program in Northern Virginia. People who have had chickenpox are at risk of developing the burning, itchy rash years or decades later. Long-term, debilitating nerve pain, called postherpetic neuralgia, is the most common complication of shingles because the varicella-zoster virus hides in the peripheral nervous system. It’s not that the shingles vaccine itself is a “magic pill,” Pauldurai said. Rather, the vaccine guards against the disease, which is known to disrupt brain health. “When the brain is stressed or challenged with any kind of illness, underlying risks for dementia become more apparent,” …









