All posts tagged: Stanford Medicine

Chatbots outperform doctors in diagnosing many diseases, study finds

Chatbots outperform doctors in diagnosing many diseases, study finds

Some medical decisions do not come with a single clean answer. A doctor may know what disease a patient has, yet still face a harder question: what should happen next? Should surgery move ahead if the patient takes blood thinners? Should a medication plan change because of a bad reaction in the past? Should a suspicious lung mass be biopsied right away, watched, or investigated with more imaging first? Those judgment calls sit in the gray zone of medicine, where context matters as much as textbook knowledge. A new line of research led by Stanford Medicine suggests that large language models, or LLMs, can help there too, especially when they are built to work with physicians instead of simply spitting out answers. In a study published in Nature Medicine, researchers found that a chatbot working alone outperformed doctors who relied only on internet searches and medical references when handling complicated clinical management questions. Yet doctors who used a chatbot matched the chatbot’s performance, suggesting that the strongest results came from collaboration rather than either side …

New nasal vaccine protects lungs for months against viruses, bacteria, and allergens

New nasal vaccine protects lungs for months against viruses, bacteria, and allergens

A vaccine usually trains your immune system to recognize one target. Here, the target is basically “anything that doesn’t belong in the lungs.” That is the surprising promise behind a new mouse study from Stanford Medicine researchers and collaborators. The team reports an intranasal vaccine formula that protected mice for months against several respiratory viruses, two bacteria that often cause hospital infections, and even an allergen linked to asthma. The findings are published in Science. “I think what we have is a universal vaccine against diverse respiratory threats,” said Bali Pulendran, PhD, the Violetta L. Horton Professor II and a professor of microbiology and immunology at Stanford. Haibo Zhang, PhD, a postdoctoral scholar in Pulendran’s lab, is the study’s lead author. Bali Pulendran, Violetta L. Horton Professor, Director, Institute for Immunity, Transplantation and Infection and Professor of Microbiology and Immunology. (CREDIT: Jim Gensheimer) A different bet than “match the antigen” For more than two centuries, vaccine design has leaned on one big idea: antigen specificity. You show the body a harmless version of a pathogen’s …