Scientists identify five distinct phases of brain structure across the human lifespan
New research indicates that the structural organization of the human brain does not develop in a continuous, linear fashion but rather progresses through five distinct phases separated by specific turning points. By analyzing brain scans from thousands of individuals ranging from infants to ninety-year-olds, scientists identified significant shifts in neural architecture occurring around ages nine, 32, 66, and 83. These findings, published in Nature Communications, provide a new framework for understanding how the brain reorganizes itself throughout the human lifespan and suggests that structural adolescence may extend well into the third decade of life. Previous research has established that brain structure and function evolve as people age. However, many of these studies focused on specific developmental windows, such as early childhood or old age, rather than the entire life course. When studies did examine broader age ranges, they often relied on models that assumed smooth, gradual trajectories, such as a simple peak in adulthood followed by a steady decline. The authors of the new study argued that these approaches might miss complex, non-linear shifts in …








