All posts tagged: worsen

25-year-long study discovers how blood cancers evolve and worsen

25-year-long study discovers how blood cancers evolve and worsen

Some blood cancers move with eerie patience. A patient can feel well for years, their blood counts looking steady, their daily life mostly intact. Yet deep inside the bone marrow, tiny genetic shifts may already be setting the course for something much worse. New research suggests those shifts can appear long before doctors see clear clinical signs that a disease is speeding up. That matters for people living with myeloproliferative neoplasms, or MPNs, a group of rare chronic blood cancers that begin in the bone marrow. These cancers cause the body to make blood cells in an uncontrolled way. In the UK, about 40,000 people live with these conditions, and roughly 4,000 new cases are diagnosed each year. Blood cancers with long timelines MPNs often unfold over decades. They are usually driven by mutations in genes such as JAK2, CALR or MPL. Though around 10 percent of patients do not carry those usual markers. Some remain stable and need only gentle treatment. Others go on to develop myelofibrosis, which scars the bone marrow. Or, they …

IMF Warns Iran War Will Slow Global Growth, Raise Inflation, And Worsen Food Insecurity

IMF Warns Iran War Will Slow Global Growth, Raise Inflation, And Worsen Food Insecurity

Submitted by OilPrice.com Severe fuel shortages, hunger, and spiralling inflation will be some of the consequences of the Iran war as the head of the International Monetary Fund said that it would leave “scarring effects” on the global economy.   In a speech by Kristalina Georgieva, the IMF’s managing director, global policymakers were warned that trade disruption across the Middle East over the last month would lead to lower growth and higher inflation. IMF Başkanı Kristalina Georgieva, İran savaşının küresel ekonomik büyümeyi yavaşlatacağı konusunda uyarıda bulundu. pic.twitter.com/KJjRWlQvYl — Voice Of Middle East (@VOME_TR) April 10, 2026 The impact of the war was also predicted to be uneven between different countries depending on levels of energy imports and their proximity to the war, according to the world’s foremost economic organisation. Georgieva’s address on Thursday morning underlined the consequences of what one month of the US and Israel’s war with Iran, and the subsequent hold-up in trading flows across the Strait of Hormuz, would mean for the world economy.  She warned that the most severe fuel disruptions will …

Depression in early adolescence is linked to attention problems that worsen over time

Depression in early adolescence is linked to attention problems that worsen over time

A new study published in the Journal of Affective Disorders provides evidence that while depression in early adolescence is linked to various cognitive difficulties at first, most of these issues do not persist as teens grow older. The exception is inattention, which tends to fuel a two-way relationship where poor attention worsens depression and vice versa. These findings suggest that addressing attention problems in school could be an effective way to help adolescents struggling with their mental health. Depression is a major mental health concern that affects roughly eight percent of adolescents worldwide. As young people move through middle and high school, depression can negatively impact their relationships, physical health, and academic performance. Scientists recognize that depression in adults often comes with cognitive impairment, meaning difficulties with thinking, remembering, and concentrating. When looking at adolescents, previous studies have provided mixed results regarding whether depression causes similar cognitive problems. Most prior research on young people has been cross-sectional. A cross-sectional study looks at a single moment in time. Because of this design, past research could not …

Menstrual hormones may worsen ADHD symptoms in medicated women

Menstrual hormones may worsen ADHD symptoms in medicated women

Women managing attention-deficit hyperactivity disorder with stimulant medications might experience worse symptoms during certain phases of their menstrual cycle. A recent study published in the Journal of Attention Disorders tracked daily symptom severity in adult females taking amphetamines. Tracking data revealed that ADHD symptoms and negative mood peak during the menstruation phase, pointing toward a need for personalized treatment plans that account for hormonal fluctuations. Attention-deficit hyperactivity disorder affects approximately six percent of the adult population. The condition is characterized by chronic difficulties with focus, elevated impulsivity, and physical hyperactivity. Patients often struggle to manage their time, organize daily tasks, or regulate their emotional responses in demanding environments. Males historically received the diagnosis at much higher rates than females, often at a ratio of three boys for every one girl. That diagnostic gap is steadily narrowing as clinicians better recognize how the condition presents in adult women. Females often express higher levels of inattentiveness and internalizing behaviors rather than outward physical hyperactivity. This difference in symptom presentation often causes teachers and parents to miss the …

Air pollution might worsen children’s vision

Air pollution might worsen children’s vision

AI model: Short for artificial-intelligence model, it’s a particularly smart computer algorithm. Simple types of these models choose from a set of pre-selected to answer a user’s requests (perhaps to respond to a chat). More complex models may train on mountains of data to essentially figure out their own answers to potentially novel questions. artificial intelligence: A type of knowledge-based decision-making exhibited by machines or computers. The term also refers to the field of study in which scientists try to create machines or computer software capable of intelligent behavior. blood vessel: A tubular structure that carries blood through the tissues and organs. cell: (in biology) The smallest structural and functional unit of an organism. Typically too small to see with the unaided eye, it consists of a watery fluid surrounded by a membrane or wall. Depending on their size, animals are made of anywhere from thousands to trillions of cells. coauthor: One of a group (two or more people) who together had prepared a written work, such as a book, report or research paper. Not …

Vanishing Y chromosomes could aid or worsen lung cancer outcomes

Vanishing Y chromosomes could aid or worsen lung cancer outcomes

Understanding how losing the Y chromosome affects treatment outcomes in lung cancer could guide therapy decisions da-kuk/Getty Images Men with the most common form of lung cancer seem to be uniquely susceptible to losing the Y chromosome from their cells, which could have advantages and disadvantages. On the one hand, it shields their tumours from being destroyed by the immune system, but on the plus side, it boosts the effectiveness of a commonly used cancer drug. As men age, many of their cells are prone to mutating and losing their Y chromosomes. With immune cells, this has been linked to heart disease and a shorter lifespan. Evidence is also accumulating that cancerous cells shedding their Y chromosomes affects the condition’s progression, with bladder cancers being the best-studied example. For a cell, loss of Y is a binary event: it either happens or it doesn’t. But what seems to be important for health outcomes is the fraction of cells of a particular type that lack a Y chromosome. The latest research began with Dawn DeMeo at …