All posts tagged: jabs

Genetics may help explain why results from weight-loss jabs vary, say scientists | Weight-loss drugs

Genetics may help explain why results from weight-loss jabs vary, say scientists | Weight-loss drugs

Scientists have discovered how genetics may help explain why weight-loss jabs work better for some people than others. Variations in two genes involved in gut hormone pathways, which regulate appetite and digestion, may help account for different weight-loss results or side-effects when taking glucagon-like peptide 1 (GLP1) medicines. The findings, published in the journal Nature on Wednesday, could support future efforts to use genetic information when making treatment choices for obesity. GLP1 receptor agonists, including semaglutide (known by the brand name Wegovy) and tirzepatide (marketed as Mounjaro), are medicines that mimic natural gut hormones. The drugs, which help regulate appetite, insulin release and digestion, are used by millions of people worldwide to treat obesity. However, the reasons why some lose more weight than others, or why some experience side-effects, have remained elusive. Researchers from 23andMe, a nonprofit medical research institute, studied data from 27,885 patients on GLP1 drugs. They found that the GLP1 receptor variant rs10305420 was associated with slightly more weight loss in those carrying this variant compared with those who lacked it. Another …

Donna Ashworth exclusive: ‘The noise around weight loss jabs can be triggering after battling anorexia – but I’ve found tools to cope’

Donna Ashworth exclusive: ‘The noise around weight loss jabs can be triggering after battling anorexia – but I’ve found tools to cope’

When poet Donna Ashworth bounced into the Second Act podcast studio she was like a ray of sunshine, full of positivity and vitality.  The bestselling poet revealed she has finally, aged 50, managed to find ways to tweak her brain and lead a relatively peaceful life which, having suffered from anorexia and OCD,  since she was a schoolgirl, feels like a massive feat. It was a deeply personal chat and what she was keen to share was that being aware of the triggers that can lead into these conditions is the first step in getting help and taking back control of your busy mind. By sharing her emotional story she hopes she will help others become aware earlier of potential issues that need to be dealt with, and then seek help before it spirals out of control. Donna Ashworth with Ateh Jewel in the Second Act studio With the rise in people getting easy access to weight loss jabs, Donna feels that, now more than ever, people who have suffered from anorexia are feeling vulnerable …

Farmers left with ‘potato mountains’ as fat jabs hit demand

Farmers left with ‘potato mountains’ as fat jabs hit demand

Farmers and fish‑and‑chip shops across the UK report falling demand for potatoes, partly blaming weight‑loss jabs like Ozempic and Mounjaro. Grower Andy Goodacre says he may have to dump 600 tonnes after major buyers cut orders. Chip shops also note customers choosing smaller portions and sharing chips. Producers warn that if current demand stays low, future potato planting may also decline. Source link

Weight loss jabs may help with anxiety and depression, study finds | UK News

Weight loss jabs may help with anxiety and depression, study finds | UK News

Drugs used for weight loss could help reduce anxiety and depression, a new study revealed. Ozempic and Wegovy, which are two common obesity jabs, may help alleviate the symptoms of mental health conditions. They can also help cut the risk of drug abuse and binge drinking, scientists discovered. An international team of experts analysed the impact these medications had on mental health issues, using data on patients diagnosed with anxiety or depression. They studied figures from Sweden on more than 95,000 people over a 13-year period, including 22,480 who used semaglutide – the active ingredient in both Ozempic and Wegovy. Image: Wegovy weight loss drug packet with needles. Pic: PA Both were linked with a lower risk of worsening mental illness compared to those who didn’t use the injections, the scientists found. Semaglutide was associated with a 44% lower risk of worsening depression and a 38% decreased risk of worsening anxiety. It was also linked to a lower risk of substance abuse, the experts said. Another active ingredient known as liraglutide, which is used in …

Patton Oswalt Jabs Timothée Chalamet Over Ballet and Opera Comments

Patton Oswalt Jabs Timothée Chalamet Over Ballet and Opera Comments

The audience at the 73rd Motion Picture Sound Editors Golden Reel Awards got a kick out of Patton Oswalt‘s cracks regarding Timothée Chalamet‘s controversial remarks about ballet and opera. Hosting the MPSE ceremony Sunday in Los Angeles for the fourth straight year, Oswalt kicked off the festivities that celebrated sound design. The comedian’s monologue began with quips that called attention to the ongoing debate surrounding Chalamet having told Matthew McConaughey last month during a Variety and CNN town hall that he would not want to be involved in an art form that “no one cares about” and is struggling to stay alive, citing ballet and opera as examples. “Thank God we’re here to celebrate achievement in sound editing and not watching ballet or the opera,” Oswalt said. He added with a laugh, “Thank God we are actually watching something that deserves to be alive.” The jokes led to plenty of laughter from the audience, in addition to some groans. The host then noted, “He said it after they were done voting. He’s fine. He’s safe.” Although Chalamet …

Stopping weight loss jabs can lead to rapid weight regain in one year, study suggests | Science, Climate & Tech News

Stopping weight loss jabs can lead to rapid weight regain in one year, study suggests | Science, Climate & Tech News

People on obesity jabs will regain the majority of the weight they lose within a year of stopping the drugs, a new study suggests. Researchers at the University of Cambridge found that after stopping the jabs for 52 weeks, on average people had regained 60% of the weight they lost. They warned that if the regained weight is mainly fat, patients could “be worse off than before” they started the jabs. How do the drugs work? Weight loss jabs are a class of drugs known as GLP-1 receptor agonists, which work by mimicking the hormone GLP-1 to regulate blood sugar and insulin levels. Originally developed as a treatment for type 2 diabetes, certain types, such as semaglutide (Wegovy) and tirzepatide (Mounjaro), are approved for use on the NHS to help tackle obesity. The jabs could also be used to prevent and treat addiction to alcohol, cigarettes and drugs like cannabis, cocaine, nicotine and opioids, a second study involving more than 600,000 US veterans with type 2 diabetes suggests. Experts believe the way the GLP-1 receptor …

Cardi B claps back at DHS with jabs over Epstein files and ICE raids

Cardi B claps back at DHS with jabs over Epstein files and ICE raids

Get the inside track from Roisin O’Connor with our free weekly music newsletter Now Hear This Get our free music newsletter Now Hear This Get our free music newsletter Now Hear This Cardi B got embroiled in a war of words with the Department of Homeland Security on social media after jokingly telling fans on the opening night of her new U.S. tour that she’s prepared to use “bear mace” to ward off ICE agents. The New York City-born rapper, 33, kicked off her latest run of shows Wednesday night in Palm Desert, California. During the concert, she reportedly sang a snatch of the traditional Mexican folk song “La Cucaracha” before asking if there were any Guatemalans or Mexicans in the audience. In fan-shot footage of the concert, the “WAP” rapper can be heard adding: “B****, if ICE come in here we’re gonna jump their asses. B****, I’ve got some bear mace in the back. They ain’t taking my fans, b****!” She then launched into her 2018 single “I Like It,” a collaboration with Colombian …