Obesity does not just enlarge fat stores, it appears to rework the body’s wiring and immune landscape in ways scientists have struggled to see. Now, whole-body mouse maps point to damaged facial sensory nerves, and to inflammatory hotspots with wider implications. Obesity is easy to spot on a scale. What has been much harder to see is how deeply it reshapes the body beneath the surface. This ranges from immune-cell buildups in swollen tissue to subtle damage in nerves that help animals sense the world around them. That blind spot may now be narrowing. A research team led by Prof. Ali Ertürk of Helmholtz Munich and Ludwig Maximilians University Munich (LMU) has developed a whole-body imaging and analysis system called MouseMapper. This deep-learning framework can scan intact transparent mice and automatically map nerves, immune cells, organs, and tissues across the body. In obese mice, the approach turned up widespread inflammatory changes. In addition, it revealed an unexpected form of nerve remodeling in the face. The work pushes past a long-standing problem in obesity research. Scientists …