All posts tagged: regain

Stopping weight loss jabs can lead to rapid weight regain in one year, study suggests | Science, Climate & Tech News

Stopping weight loss jabs can lead to rapid weight regain in one year, study suggests | Science, Climate & Tech News

People on obesity jabs will regain the majority of the weight they lose within a year of stopping the drugs, a new study suggests. Researchers at the University of Cambridge found that after stopping the jabs for 52 weeks, on average people had regained 60% of the weight they lost. They warned that if the regained weight is mainly fat, patients could “be worse off than before” they started the jabs. How do the drugs work? Weight loss jabs are a class of drugs known as GLP-1 receptor agonists, which work by mimicking the hormone GLP-1 to regulate blood sugar and insulin levels. Originally developed as a treatment for type 2 diabetes, certain types, such as semaglutide (Wegovy) and tirzepatide (Mounjaro), are approved for use on the NHS to help tackle obesity. The jabs could also be used to prevent and treat addiction to alcohol, cigarettes and drugs like cannabis, cocaine, nicotine and opioids, a second study involving more than 600,000 US veterans with type 2 diabetes suggests. Experts believe the way the GLP-1 receptor …

‘I don’t want to micromanage my body’: how the adjustable waistband became a way to regain control | Fashion

‘I don’t want to micromanage my body’: how the adjustable waistband became a way to regain control | Fashion

I always think that the most stylish woman in a room is the one who looks the most comfortable. She might be nonchalant in a pair of wide trousers and a loose white shirt, or stroll in casually wearing the butter-soft leather loafers she’s had for years. It was a longing to be more like one of those women, as opposed to one who fell over regularly in public because I couldn’t balance in platforms, which made me give up wearing heels for good in 2012. So it was a natural progression, a decade later, to shunning another wardrobe constraint that was making me fidget in social situations: the waistband. The Guardian’s journalism is independent. We will earn a commission if you buy something through an affiliate link. Learn more. I’m about to turn 49 and in the past eight years I’ve been fluctuating between sizes 10 and 14, which is hardly surprising when you consider that the average British woman may change dress size a whopping 31 times in her adult life. I attribute my …

Weight regain seems to occur within 2 years of stopping obesity drugs

Weight regain seems to occur within 2 years of stopping obesity drugs

Weight-loss drugs like Mounjaro (tirzepatide) are very effective – so long as you actually take them Allan Swart / Alamy People who stop taking weight-loss drugs tend to regain the weight they lost within less than two years, according to a study of more than 9000 people. Some argue that this emphasises that obesity is a chronic condition that requires long-term treatment. “These drugs are highly effective but obesity is a chronic, relapsing condition,” Susan Jebb at the University of Oxford said at a press briefing. “One would expect that these treatments need to be continued for life, just in the same way as blood pressure medication.” Weight-loss drugs have undoubtedly helped to tackle obesity. This is particularly the case for newer GLP-1 medications – which mimic a gut hormone called glucagon-like peptide-1 – such as semaglutide, sold as Ozempic and Wegovy, and tirzepatide, sold as Mounjaro and Zepbound. Such drugs also impact our health in other ways, such as by lowering blood pressure and cholesterol levels. But many people come off GLP-1 drugs due …