Blood-based aging clock predicts dementia risk years before symptoms
A person’s body can age faster than the calendar suggests, and that gap may carry important clues about dementia risk. In a study of more than 220,000 UK Biobank participants, researchers at King’s College London found that people whose biological age appeared older than their chronological age were more likely to develop dementia over time. They were also more likely to develop it sooner. The pattern was especially strong for vascular dementia, a form linked to reduced blood flow in the brain. The work points to a simple idea with large consequences. Two people may be the same age on paper, but one may show signs of faster internal aging in the blood. That difference, the researchers say, could help identify people who face a greater chance of dementia before symptoms begin. “Our findings suggest that biological ageing data can help identify individuals at risk of dementia before clinical symptoms emerge,” said lead author Dr. Julian Mutz, King’s Prize Research Fellow at the Institute of Psychiatry, Psychology & Neuroscience at King’s College London. “By combining …
