A Startup Says It Grew Human Sperm in a Lab—and Used It to Make Embryos
The goal, he says, is to create thousands of sperm from a standard tissue biopsy. The company has had a high success rate in generating sperm from dozens of tissue samples. Pastuszak says early testing shows the lab-made sperm look “effectively identical” to naturally made sperm. The procedure is not yet ready to be used to start pregnancies, though. Paterna created embryos as an early test to validate that its lab-made sperm was actually viable. The company plans to conduct a larger, more comprehensive study involving men with infertility. Paterna will extract sperm from their ejaculate or testicular tissue and use its method to generate sperm for the men. From there, the company will use both the extracted sperm and lab-made sperm to fertilize eggs in the lab, compare fertilization rates between the two groups, and analyze the resulting embryos for physical and genetic abnormalities. “That will actually tell us a ton regarding the efficacy and safety of the approach. It will tell us if there are any mutations that are created by the in …
