Embryos made without sperm or eggs reveal why many pregnancies fail
Embryo models closely resemble early human embryos SCIEPRO/SCIENCE PHOTO LIBRARY/Alamy Inside a lab in Vienna, cells are dividing to form a hollow sphere. Although the fragile ball has all the characteristics of an early human embryo, it isn’t quite what it seems. It didn’t, in fact, begin with an egg meeting a sperm. Instead, it was created entirely in the lab. The very first days of pregnancy have long been an enigma. Scientists are unable to peer inside the uterus during pregnancy, meaning we know little about why so many fail. This is now beginning to change, thanks to embryo models created from stem cells, which are lifting the lid on one of the great mysteries of human biology. In the five years since early human embryo models known as blastoids were first created in several labs – including the one in Vienna – researchers have dramatically advanced our understanding of the early days of life. This is already leading to improvements for in vitro fertilisation (IVF) and treatments for serious conditions that occur during …









