When Lydia Clarke and Reed Herrick opened their cheese shop in 2013, it was the realization of a years-long dream and part of an early wave of restaurants and stores underpinning what many called downtown’s renaissance. But after more than 12 years in business, Clarke and Herrick are shuttering DTLA Cheese Superette. Friday will be its last day. Their next-door wine bar, Kippered, remains open. “It was a tidal wave of factors that bear down on you,” Herrick said earlier this week about the closure. “This is a process that has been happening for years. Nobody is spending, there are protests, strikes, war, all of it comes to bear here.” A selection of cheeses in the central refrigerated case at DTLA Cheese Superette, which first opened more than 12 years ago in Grand Central Market downtown. (Jennelle Fong) Clarke and her sister, Marnie, who is also a partner, are third-generation dairy purveyors whose family founded Alta Dena Dairy. Cheese was more than a calling; it seemed like a birthright. They opened DTLA Cheese in Grand …