The potential of Bdellovibrio bacteriovorus as a ‘living antibiotic’
Following her successful application for an ERC Starting Grant, Simona Huwiler discusses the potential of Bdellovibrio bacteriovorus, a predatory bacterium, to address the growing concern of antibiotic resistance. The public health implications of antimicrobial resistance are concerning. A recent study by the World Health Organization (WHO) in its 2025 Global AMR Surveillance Report indicated that 1 in 6 bacterial infections worldwide in 2023 were resistant to antibiotics. Another study examining data from 2019 reported that approximately 5 million deaths were associated with AMR. Among these, around 3 million deaths were directly attributable to antimicrobial resistance. This widespread occurrence of antimicrobial resistance makes it increasingly difficult to treat bacterial infections in hospitals, while also posing a threat to various medical procedures such as surgeries and cancer treatments. Currently, the goal is to prevent the inappropriate use of antibiotics, particularly in cases where they are ineffective. Many governments are working to restrict the use of last-resort antibiotics in animal farming, as they are essential for treating certain infections. In some countries, antibiotics can be obtained without a …
